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Cloud/Government Technology/News
FedRAMP Kicks Off 20x Phase 2 Pilot With Cohort 1 Selection
by Jane Edwards
Published on December 11, 2025
FedRAMP logo. FedRAMP announced three cloud services participating in Cohort 1 of the 20x Phase 2 pilot.

The Federal Risk and Authorization Management Program has announced the three cloud services participating in the first cohort of FedRAMP 20x Phase 2 pilot.

FedRAMP said Wednesday 20x Phase 2, which was first announced in September, required cloud services to submit pilot proposals demonstrating their planned approach in advance.

The cloud services selected for Cohort 1 of the FedRAMP 20x Phase 2 pilot are Confluent Cloud for Government, Meridian LMS and Paramify Cloud.

Table of Contents

  • What’s Next for FedRAMP 20x in 2026?
  • What Is FedRAMP 20x?

What’s Next for FedRAMP 20x in 2026?

FedRAMP Director Pete Waterman shared an open letter to the FedRAMP Board highlighting the next steps for the 20x Phase 2 pilot program.

Upcoming efforts include:

  • Review of proposals for Phase 2, Cohort 2: From Jan. 5 to 9, FedRAMP will review pilot proposals from eligible 20x Phase 2 pilot participants and will select up to seven participants to take part in the Phase 2 pilot.
  • Transition to Phase 3: Phase 2 will conclude at the end of the second quarter of fiscal year 2026, paving the way for broader adoption of 20x improvements in the third and fourth quarters of FY 2026 under Phase 3.
  • AI Authorizations: FedRAMP plans to finalize the first three AI Prioritization 20x Low authorizations in January.
  • Innovation through partnerships: FedRAMP will continue hosting quarterly FedRAMP Days.

What Is FedRAMP 20x?

FedRAMP 20x is a cloud-native authorization framework designed to advance the use of automation to accelerate the authorization process and facilitate secure cloud adoption across federal agencies.

Under the initiative, cloud service providers are encouraged to establish their security goals, continuously validate the effectiveness of the capabilities used to meet those goals and measure their performance against those goals. 

Through this framework, CSPs secure authorization to enhance their service offerings without needing permission for significant changes.

Cybersecurity/News
Legislators Reintroduce Bipartisan Satellite Cybersecurity Act Amid Rising Space-Based Threats
by Elodie Collins
Published on December 11, 2025
Satellites in orbit. Senate legislators have introduced a bill to secure satellites from cyberthreats

Sens. Gary Peters, D-Mich., and John Cornyn, R-Texas, have reintroduced a bipartisan bill to support satellite owners and operators against growing cybersecurity threats to space assets.

Legislators Reintroduce Bipartisan Satellite Cybersecurity Act Amid Rising Space-Based Threats

American systems are being targeted by adversaries. Gain better understanding of emerging cyberthreats to the nations and learn directly from government and industry experts at the Potomac Officers Club’s 2026 Cyber Summit on May 21. Click here to secure your tickets.

Table of Contents

  • What Is the Satellite Cybersecurity Act?
  • When Else Have the Senators Introduced the Satellite Cybersecurity Act?

What Is the Satellite Cybersecurity Act?

The Satellite Cybersecurity Act tasks the Department of Commerce to provide voluntary cybersecurity recommendations and establish an online clearinghouse to streamline access to information on how to secure space systems, the Senate said Wednesday.

The bill also tasks the Government Accountability Office to examine programs to secure commercial satellites and identify ways to integrate satellite capabilities into critical infrastructure sectors.

Peters, a ranking member of the Senate’s Homeland Security and Governmental Affairs Committee, said in a statement that the Satellite Cybersecurity Act will enable companies to protect their satellite systems from cyberthreats.

“Foreign adversaries and cybercriminals continue to target cybersecurity vulnerabilities in commercial satellites, and these attacks have the potential to significantly disrupt American lives and livelihoods,” he warned.

Cornyn added that the bipartisan bill will provide satellite operators with the tools they need to safeguard their systems against disruptions caused by bad actors.

When Else Have the Senators Introduced the Satellite Cybersecurity Act?

Peters and Cornyn have introduced the Satellite Cybersecurity Act two other times, most recently in 2023. The Record reported that the bill advanced out of the Homeland Security Committee both times but did not receive votes once it moved to the Senate floor.

DoD/News
House Passes FY26 Defense Spending Bill Authorizing $900.6B
by Elodie Collins
Published on December 11, 2025
The Department of War's logo. House passed a spending bill for DOW

The House of Representatives voted 312-112 to pass the National Defense Authorization Act, authorizing a $900.6 billion funding for the Pentagon for fiscal year 2026, Breaking Defense reported.

The bill increases the pay of service members, approves military aid for Ukraine, and finances shipbuilding and procurement of aircraft, ground vehicles and munitions.

House Passes FY26 Defense Spending Bill Authorizing $900.6B

Learn more about the technologies that reinforce the U.S. military’s edge over adversaries at the Potomac Officers Club’s 2026 Defense R&D Summit on Jan. 29. The event will feature leaders from across the Department of War and the GovCon industry to deliver insights into the present and future of warfare. Secure your tickets to this highly anticipated networking event today.

Table of Contents

  • How Will NDAA FY26 Affect Military Procurement Processes?
  • What Programs Will NDAA FY26 Fund?

How Will NDAA FY26 Affect Military Procurement Processes?

Additionally, the new NDAA includes provisions that impact the U.S. military’s capability procurement programs.

The NDAA marks the Department of War’s shift from the current program executive officer, or PEOs, to a portfolio acquisition executive, or PAE.

According to previously released department documents, the PAE will oversee multiple programs and will be in charge of allocating resources across systems to ensure timely delivery.

In November, the Army announced the establishment of six PAEs under Army Transformation and Training Command and the assistant secretary of the Army for acquisition, logistics and technology.

The NDAA also includes language to halt the Air Force’s retirement of its A-10 Thunderbolt II fleet and divest F-15E Strike Eagle aircraft over the next year. In contrast, the bill is preventing the Pentagon from canceling the E-7 Wedgetail program.

For the Army, the bill greenlights the acquisition of UH-60 Black Hawk and the early production of the Future Long-Range Assault Aircraft.

What Programs Will NDAA FY26 Fund?

NDAA authorizes over $25 billion for the purchase of critical munitions, including Naval Strike Missiles, Tomahawks, Javelins, Sidewinders and Advanced Medium Range Air-to-Air Missiles.

The bill also provides the Pentagon $26 billion in shipbuilding funds for the purchase of Columbia-class ballistic missile and Virginia-class submarines, Arleigh Burke-class destroyers, ship-to-shore connector landing craft, and other vessels.

President Donald Trump’s Golden Dome will also receive funding under the policy bill.

DoD/Government Technology/News
DIU, USINDOPACOM Select 10 Startups for Blue Object Management Accelerator
by Miles Jamison
Published on December 11, 2025
DIU logo. DIU has chosen 10 startup teams to participate in the first Blue Object Management Challenge Accelerator.

The Defense Innovation Unit has announced the 10 startup teams that will participate in the first Blue Object Management Challenge Accelerator.

Table of Contents

  • What Is the Blue Object Management Challenge Accelerator?
  • Which Companies Were Selected for the 2025 Cohort?

What Is the Blue Object Management Challenge Accelerator?

The Blue Object Management Challenge, launched in August, seeks to rapidly discover and prototype commercial technologies that align with the operational priorities of the U.S. Indo-Pacific Command, or USINDOPACOM, in the Indo-Pacific region, DIU said Wednesday.

The term “blue objects” refers to U.S. forces, systems and facilities in military operations. The initiative prioritizes tracking and managing these assets in real time to ensure commanders have accurate operational insight.

Which Companies Were Selected for the 2025 Cohort?

The 2025 cohort is composed of 10 companies competitively selected through DIU’s prize challenge process for their work in advancing artificial intelligence-driven decision-making to enhance the integration, accessibility and use of mission-critical data across Department of War platforms and forces.

The selected participants include CI-PHER Tech, Countifi, Dunedain Systems, Exia Labs, Kinnami Software, Lumbra, MAIK, Snorkel AI, Unstructured Technologies and Valinor Streamline. Each one will receive a portion of the $500,000 prize pool. During the 12-week accelerator program, the teams will collaborate with DIU and USINDOPACOM to test, validate and transition their projects.

Artificial Intelligence/News
DOE Announces $320M Investment to Advance Genesis Mission AI
by Miles Jamison
Published on December 11, 2025
DOE seal. DOE has announced a $320 million investment for accelerating the development of Genesis Mission's AI capabilities.

The Department of Energy has disclosed an investment exceeding $320 million intended for accelerating the development of Genesis Mission’s artificial intelligence capabilities.

DOE Announces $320M Investment to Advance Genesis Mission AI

Explore the ways AI is enabling government, military and the GovCon industry to process data and accomplish intricate missions at the Potomac Officers Club’s 2026 Artificial Intelligence Summit on March 19.

What Is the Genesis Mission & Its Key Initiatives?

The Genesis Mission is a DOE-led initiative focused on leveraging AI to advance U.S. energy dominance, strengthen national security and fast-track scientific discovery. The funding will support four key initiatives of the program, including the American Science Cloud, which will host and distribute AI models and scientific data for the research community, and the Transformational AI Models Consortium, which will create self-improving AI models for science, engineering and energy missions.

The investment will fund 14 projects in robotics, automated laboratories and autonomous control of large-scale experiments. These projects aim to transform laboratory environments and scientific experiments with intelligent systems leveraging embodied AI, advanced automation and robotics. Additionally, the program will support 37 foundational AI projects focused on organizing and preparing massive amounts of existing scientific data and developing powerful and reliable AI models that are rigorously tested for scientific use.

“Thanks to President Trump’s Working Families Tax Cut, the Department of Energy is proud to advance AI investments to ensure American technological leadership and accelerate scientific discovery,” said Dario Gil, under secretary for science and innovation at DOE. ”By investing in the American Science Cloud and the Transformational AI Model Consortium we are creating the foundational technologies and AI-ready data sets that will enable the success of the Genesis Mission.”

Artificial Intelligence/News/Space
NASA JPL Opens New Center to Accelerate Moon, Mars Missions Through AI Partnerships
by Kristen Smith
Published on December 11, 2025
Moon. NASA's JPL has launched a new Rover Operations Center to support missions to the moon and Mars.

NASA’s Jet Propulsion Laboratory has opened a new Rover Operations Center, serving as a central hub for mission operations and a mechanism to support the space technology development efforts of commercial space and artificial intelligence organizations.

JPL said Wednesday that the facility is designed to consolidate its planetary surface mission expertise and expand the use of autonomous systems across upcoming lunar and Mars programs. 

Representatives from commercial space and AI companies joined JPL personnel during the facility’s inauguration for technical discussions and demonstrations.

Table of Contents

  • How Will the ROC Support Future Moon and Mars Missions?
  • What Role Will AI Play in the New JPL Operations Center?
  • How Will Industry Benefit from the ROC?

How Will the ROC Support Future Moon and Mars Missions?

JPL leadership described the ROC as a means to increase mission efficiency and broaden access to the lab’s operational capabilities. The facility provides a centralized structure for engineering support, mission planning, training, anomaly response and integration activities for rover and aerial systems.

“The Rover Operations Center is a force multiplier,” said Dave Gallagher, director at JPL. “It integrates decades of specialized knowledge with powerful new tools, and exports that knowledge through partnerships to catalyze the next generation of Moon and Mars surface missions.”

What Role Will AI Play in the New JPL Operations Center?

A primary focus of the ROC is accelerating the adoption of advanced autonomy in surface missions. The center is already applying AI to operational workflows, including a recent demonstration in which the Perseverance team used generative AI to explore possible future driving routes on Mars.

The effort builds on JPL’s long-running autonomy development. Past milestones include the introduction of autonomous task scheduling on Perseverance and the earlier evolution of rover independence dating back to Sojourner in the 1990s.

Matt Wallace, head of JPL’s Exploration Systems Office, said the mission environment demands faster advancement. “Our rovers are lasting longer and are more sophisticated than ever before. It’s time to take our game up a notch and bring everybody we can with us.”

How Will Industry Benefit from the ROC?

As NASA’s federally funded research and development center, JPL is positioned to enable technology transfer and collaborative development. Through the ROC, JPL aims to deliver new mission-enabling technologies such as digital engineering models, mission-adapted AI tools and autonomy stacks designed for edge computing environments.

DoD/News
DOW’s Massive Increase in RDT&E Funding—What GovCons Should Know
by Pat Host
Published on December 11, 2025
Gabe Camarillo. The KBR senior VP and 4x24 member discussed the Pentagon's FY 2025 RDT&E budget request.

The Pentagon’s colossal $179 billion request for research, development, test and evaluation funding in FY 2026 isn’t just a 20 percent increase from the $141 billion enacted in FY 2025. It’s also a bellwether for which technologies the Department of War views as critical to U.S. success in combat over the next five-to-15 years.

Some of the most eye-popping increases in the DOW’s RDT&E request are for key emerging technologies: hypersonics; space-based intelligence, surveillance and reconnaissance; resilient missile warning and tracking in low earth orbit and agile electronic warfare and unmanned system development.

Learn the latest RDT&E business opportunities directly from top DOW officials at the Potomac Officers Club’s 2026 Defense R&D Summit on Jan. 29! Check out our multiple panels on how the DOW plans to leverage this boost in RDT&E funding to help emerging technologies get past the dreaded “valley of death” and into warfighters’ hands. Secure your seat today!

Let’s dive into these budget increases and what they would mean for DOW combat effectiveness if enacted.

Table of Contents

  • What Is the Pentagon Prioritizing in RDT&E?
  • What Is RDT&E?
  • How Will Acquisition Reform Impact DOW R&D Efforts?
  • Which Services Will Benefit Most from the Pentagon RDT&E Increases?

What Is the Pentagon Prioritizing in RDT&E?

  • Hypersonics. The $803 million requested for the Hypersonic Attack Cruise Missile prototyping would be a 72 percent increase over the $467 million provided in FY 2025. This hints that HACM is advancing toward fielding and not just experimentation, according to Defense One.
  • Space-based ISR. The $1.1 billion request for the Ground Moving Target Indicator would be a whopping 330 percent increase from the $256 million enacted in FY 2025. This reflects the DOW’s priority of better leveraging space-based ISR assets for improved performance in contested environments, instead of using airborne assets such as the Northrop Grumman E-8 Joint Surveillance Target Attack Radar System aircraft.
  • Electronic warfare and unmanned systems. A pair of Army budget lines have more than $500 million combined, suggesting a reprioritization toward improvisational effects commonly found in Ukraine, especially for counter-drone, loitering munitions and EW jamming.
Hypersonic Attack Cruise Missile. The platform is set to receive $803 million in RDT&E funding in FY 2026, 72 percent from the $467 million it received last year.
The U.S. Air Force’s Hypersonic Attack Cruise Missile (HACM) is slated to receive a 72 percent increase in FY 2026 RDT&E funding than it received in FY 2025, reflecting prioritization by the Pentagon. Photo: RTX.

What Is RDT&E?

Research, development, test and evaluation, or RDT&E, are program costs usually connected to R&D efforts, such as the development of a new or improved capability to where it can be used in the field. RDT&E is one of five core appropriations performed by the DOW. It finances RDT&E initiatives executed by both government and GovCons in the development of equipment, material or computer application software, according to the Defense Acquisition University.

The Pentagon’s RDT&E funding in not only its FY 2026 budget request, but also the One Big Beautiful Bill Act funding signed into law in mid-2025, represent a significant emphasis on accelerating the modernization of its capabilities, according to a leading GovCon executive. Gabe Camarillo, KBR senior vice president of defense technology solutions, 4×24 Leadership Series member and former Army under secretary, told ExecutiveGov in an exclusive interview that OBBBA funding provides the DOW with additional flexibility because it wasn’t put into “colors of money” like the budget request.

One example, Camarillo said, is with the Golden Dome homeland missile defense system. The roughly $150 billion provided for Golden Dome in the OBBBA will allow for the integration of the system’s components into its architecture. It will also help develop new systems to include everything from possibly space-based interceptors to new command-and-control systems enabled by AI.

Bolster your space partnership knowledge at the Potomac Officers Club’s 2026 Defense R&D Summit on Jan. 29! Hear directly from Stacie Williams, Space Force chief science officer, during her appearance on the Innovating for Advantage: Advancing Secure, Interoperable IT for Space Defense panel discussion. Don’t miss this extraordinary opportunity to grow your space portfolio revenues. Sign up now!

How Will Acquisition Reform Impact DOW R&D Efforts?

Camarillo said the Army Transformation Initiative is rooted in lessons learned from years of warfare in Ukraine, where unmanned systems are ubiquitous and the electromagnetic spectrum is highly contested. It is very difficult to avoid being seen on the battlefield in Ukraine. Additionally, the greater use of drones in Ukraine has been revolutionary.

“I think the ATI will actually be very good for R&D because I think it sends a strong signal of demand to the market that the DOW and the Army, in particular, are buying capabilities and developing them in a different way than they’ve done before,” Camarillo said.

Camarillo said these positive effects on RDT&E programs will especially kick in over the long term. This is because these acquisition reform efforts like the ATI specifically allow service leaders to identify the most promising emerging technologies and rapidly reprioritize funding within certain portfolios. Most importantly, he said, these acquisition reform initiatives use operational units to test these technologies and provide very rapid feedback, allowing service leaders to better understand which are working and which need more time to develop.

Which Services Will Benefit Most from the Pentagon RDT&E Increases?

The RDT&E budget request combined with the OBBBA funding represent a big increase in research and development funding across all Pentagon services and service-wide efforts. Camarillo said areas like Navy shipbuilding and Army drones, counter-drone, electronic warfare and autonomy stand to gain. Modernization of the nuclear triad—the air, land and sea-based legs of the DOW’s nuclear weapon infrastructure—also sets to benefit from this boost in RDT&E funding.

Industry is eagerly awaiting additional information from the DOW on Golden Dome’s architecture, which will specify which technologies the program will leverage. Camarillo said the first three things he’ll look for when Golden Dome’s architecture is announced will be:

  • What will be developed for space-based interceptors. Camarillo said Golden Dome’s architecture specifications will likely include which type of space-based interceptors will be used as part of Golden Dome’s space-based layer. It will also likely define which architecture of sensors will provide missile warning and missile tracking capabilities.
  • How the DOW will do C2, which is intended to be AI-enabled across a very diverse set of systems.
  • How to tackle the challenge of interoperability of all these new and different components and have them successfully communicate and work and operate together seamlessly.

Camarillo said Golden Dome’s architecture announcement will also specify which elements of the different layers of its architecture will be met with existing systems such as the Patriot air defense system.

DOW’s Massive Increase in RDT&E Funding—What GovCons Should Know
DoD/News/Space
NRO, SSC Launch NROL-77 Mission
by Jane Edwards
Published on December 10, 2025
National Reconnaissance Office logo. NRO and SSC have launched the NROL-77 mission aboard a SpaceX Falcon 9 rocket.

The National Reconnaissance Office and the U.S. Space Force’s Space Systems Command have launched the NROL-77 mission aboard a SpaceX Falcon 9 rocket from a launch complex at Cape Canaveral Space Force Station in Florida.

NRO said Tuesday NROL-77 marks the agency’s 10th and final launch for calendar year 2025.

Table of Contents

  • What Is the NROL-77 Mission?
  • What Is the National Security Space Launch Program?

What Is the NROL-77 Mission?

NROL-77 is the second NRO mission that the agency launched with SpaceX under the Phase 2 contract of the National Security Space Launch, or NSSL, program awarded in August 2020.

“The partnership between NRO and SSC continues to strengthen our nation’s space superiority through innovative launch solutions and shared expertise,” said Col. Kathryn Cantu, director of the NRO Office of Space Launch and NROL-77 mission director. “As space becomes increasingly contested, this partnership enables us to rapidly deploy advanced intelligence capabilities while maintaining the agility and resilience needed to address emerging threats.”

In addition to SpaceX, NRO and SSC collaborated with System Delta 80 and Space Launch Delta 45 on the mission.

What Is the National Security Space Launch Program?

NSSL is a collaborative launch acquisition program between NRO and SSC designed to ensure reliable access to space for national security missions. 

SSC’s System Delta 80 at Los Angeles Air Force Base in California oversees and operates the program.

Through the NSSL program, NRO and SSC launched two missions earlier this spring: NROL-69 in March and NROL-145 in April.

In mid-April, the agencies also launched the NROL-174 mission under the Rocket Systems Launch Program.

Artificial Intelligence/News
War Department Introduces Google’s Gemini as First GenAI.mil Offering
by Elodie Collins
Published on December 10, 2025
Emil Michael, under secretary of war for research and engineering. Michael described AI as "America's next Manifest Destiny"

The Department of War has selected Google’s Gemini for Government as the first artificial intelligence tool to be housed on its GenAI.mil platform.

The Pentagon said Tuesday that GenAI.mil was established to create an AI-first workforce that utilizes technology to enhance efficiency and combat-readiness.

“There is no prize for second place in the global race for AI dominance,” Emil Michael, under secretary of war for research and engineering commented. “We are moving rapidly to deploy powerful AI capabilities like Gemini for Government directly to our workforce. AI is America’s next Manifest Destiny, and we’re ensuring that we dominate this new frontier.”

War Department Introduces Google's Gemini as First GenAI.mil Offering

Michael will deliver a keynote speech at the Potomac Officers Club’s 2026 Defense R&D Summit on Jan. 29. Gain insights into how advanced technologies, such as AI, are shaping the modern battlefield directly from defense leader or forge meaningful partnerships with GovCon experts at this critical networking event. Secure your tickets today.

Table of Contents

  • What Will Google’s Gemini Offer to the Pentagon?
  • What Is GenAI.mil?

What Will Google’s Gemini Offer to the Pentagon?

Gemini for Government is an enterprise-grade platform built to streamline administrative tasks, such as summarizing handbooks and generating risk assessments to support operational planning. The platform offers retrieval-augmented generation and is web-grounded against Google Search to ensure reliable output .

According to Google, data inputted by DOW on the platform will not be used to train Google’s public models.

Karen Dahut, CEO of Google Public Sector and a four-time Wash100 winner, said in a statement on the company’s press release that the introduction of Gemini for Government in GenAI.mil marks a “pivotal moment for government modernization.”

“Our deep commitment to security, sovereign data protection, and the unique power of AI gives the DoW the ability to equip all of their personnel with modern tools to solve operational and productivity challenges with unprecedented speed,” she added.

Google has a OneGov agreement with the General Services Administration to provide agencies with access to Gemini for Government for a discounted price.

What Is GenAI.mil?

GenAI.mil brings generative AI capabilities to all civilians, contractors and military personnel under DOW. 

All tools that will become available on the platform are certified for DOW Impact Level 5, or controlled unclassified information.

War Secretary Pete Hegseth, a 2025 Wash100 awardee, emphasized the potential of AI to increase efficiency.

“We are pushing all of our chips in on artificial intelligence as a fighting force,” he said. “The Department is tapping into America’s commercial genius, and we’re embedding generative AI into our daily battle rhythm.”

Artificial Intelligence/Healthcare IT/News
Draper-Led Team Selected for ARPA-H CATALYST Program to Advance Human-Based Drug Safety Models
by Kristen Smith
Published on December 10, 2025
Draper logo. ARPA-H has selected a Draper-led team as a CATALYST program performer.

A Draper-led team is one of the performers selected by the Advanced Research Projects Agency for Health under its Computational ADME-Tox and Physiology Analysis for Safer Therapeutics, or CATALYST program, which aims to use human-based artificial intelligence models to predict drug safety and effectiveness earlier in the development process.

ARPA-H announced the performer teams on Thursday as part of an effort to reduce reliance on animal testing and accelerate timelines for bringing new therapies to patients.

Draper-Led Team Selected for ARPA-H CATALYST Program to Advance Human-Based Drug Safety Models

ARPA-H’s CATALYST program reflects a major shift toward AI-driven drug safety evaluation. Join top federal and industry leaders shaping that future at the 2025 Healthcare Summit on Feb. 12, 2026.

Table of Contents

  • What Work Will Draper’s Team Perform Under CATALYST?
  • How Might CATALYST Change Drug Development?

What Work Will Draper’s Team Perform Under CATALYST?

Draper said in a LinkedIn post that the Charles Stark Draper Laboratory will collaborate with Revalia Bio, researchers at Yale University and LifeShare Network to develop a human data stack that integrates multiple real-world biological data types. ARPA-H stated that the goal is to enhance understanding of how various patient groups may respond to investigational medicines before the initiation of clinical trials.

How Might CATALYST Change Drug Development?

ARPA-H stated that CATALYST will develop new computational models for predicting drug absorption, distribution, metabolism, excretion and potential toxicities. By engaging regulators and product sponsors at the outset, the program aims to facilitate the early adoption of these models in preclinical decision-making and regulatory filings.

“Too many promising medicines fail late, after years of work and enormous cost, because our best tools still don’t reliably predict how a drug will behave in people,” said Alicia Jackson, ARPA-H director. 

The program also aims to advance government efforts to develop predictive approaches that better account for populations often excluded from clinical research, including children and pregnant individuals. 

CATALYST will award up to $125 million over a period of four and a half years. ARPA-H said performer contract awards vary by team and are tied to accelerated technical milestones. Awards were made in September.

Other selected performer teams include Deep Origin, Inductive Bio and Peptilogics.

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